1. About atorvastatin

    Atorvastatin belongs to a group of medicines called statins. It's used to lower cholesterol.

    It's also taken to prevent heart disease, heart attack and stroke.

    The medicine is available on prescription. It comes as tablets, including chewable tablets, for people who have difficulty swallowing.

  2. Key facts

    • It's usual to take atorvastatin once a day.
    • The most common side effects are headaches, feeling sick, diarrhoea and cold-like symptoms.
    • Don't take atorvastatin if you're pregnant or think you could be pregnant. This medicine can harm an unborn baby.
    • Keep taking atorvastatin even if you feel well, as you will still be getting the benefits. Most people with high cholesterol don't have any symptoms.
    • Atorvastatin is also called by the brand name Lipitor.
  3. Who can and can't take atorvastatin

    Atorvastatin can be taken by adults and children over the age of 10 years.

    Atorvastatin isn't suitable for some people. Tell your doctor if you:

    • have had an allergic reaction to atorvastatin or any other medicines in the past
    • have liver or kidney problems
    • are trying to get pregnant, think you might be pregnant, you're already pregnant, or you're breastfeeding
    • have severe lung disease
    • have previously had a stroke caused by bleeding into the brain
    • drink large amounts of alcohol
    • have an underactive thyroid
    • have had muscular side effects when taking a statin in the past
    • have had, or have, a muscle disorder

    Lipitor chewable tablets contain a substance called aspartame - check with your doctor before taking these if you have phenylketonuria (an inherited disorder of protein metabolism).

  4. How and when to take it

    Take atorvastatin once a day. You can choose to take it at any time, as long as you stick to the same time every day.

    Atorvastatin doesn't upset the stomach, so you can take it with or without food.

    How much will I take?

    The usual dose for adults is between 10mg and 80mg a day.

    In children, the usual dose is 10mg to 20mg once a day. Sometimes higher doses are used - your doctor will work out the amount of atorvastatin that's right for your child.

    Your dose depends on the reason for taking it, your cholesterol levels, and what other medicines you're taking.

    Swallow atorvastatin tablets whole with a glass of water. If you've been given chewable tablets, you can chew them or swallow them whole with a glass of water.

    What if I forget to take it?

    If you occasionally forget to take a dose, take your next dose the next day at the usual time. Never take 2 doses at the same time. Never take extra doses.

    If you forget doses often, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.

    What if I take too much?

    Taking an extra dose of atorvastatin by accident is unlikely to harm you.

    Talk to your pharmacist or doctor if you're worried or take more than 1 extra dose.

  5. Side effects

    Like all medicines, atorvastatin can cause side effects in some people.

    One rare but serious side effect is unexplained muscle pain, tenderness or weakness.

    Common side effects

    These common side effects of atorvastatin happen in more than 1 in 100 people.

    Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or don't go away:

    • feeling sick
    • headache
    • pain in the back and joints
    • nosebleeds
    • sore throat
    • cold-like symptoms, such as a runny nose, blocked nose or sneezing
    • constipation, wind, indigestion or diarrhoea

    Report any unexplained muscle pain, tenderness or weakness to a doctor straight away.

    Serious side effects

    Serious side effects when taking atorvastatin are rare and happen in less than 1 in 1,000 people.

    Stop taking atorvastatin and tell a doctor if you get:

    • muscle pain, tenderness, weakness or cramps - these can be signs of muscle breakdown and kidney damage
    • yellow skin or eyes - this can be a sign of liver problems
    • a skin rash with pink-red blotches, especially on the palms of the hands or soles of the feet
    • severe tummy pain - this can be a sign of pancreas problems
    • a cough, feeling short of breath, and weight loss - this can be a sign of lung disease

    Serious allergic reaction

    In rare cases, it’s possible to have a serious allergic reaction to atorvastatin.

    A serious allergic reaction is an emergency. Contact a doctor straight away if you think you or someone around you is having a serious allergic reaction.

    The warning signs of a serious allergic reaction are:

    • getting a skin rash that may include itchy, red, swollen, blistered or peeling skin
    • wheezing
    • tightness in the chest or throat
    • having trouble breathing or talking
    • swelling of the mouth, face, lips, tongue, or throat

    These are not all the side effects of atorvastatin. For a full list see the leaflet inside your medicines packet.

    You can report any suspected side effect to the UK safety scheme.

  6. How to cope with side effects

    What to do about:

    • feeling sick - stick to simple meals and don't eat rich or spicy food. It might help to take your atorvastatin after a meal or snack.
    • headaches - make sure you rest and drink plenty of fluids. Don't drink too much alcohol
    • diarrhoea - drink plenty of water or other fluids. It may also help to take oral rehydration solutions, which you can buy from a pharmacy or supermarket to prevent dehydration.
  7. Pregnancy and breastfeeding

    Atorvastatin isn't recommended during pregnancy or breastfeeding, as there's no firm evidence it's safe.

    Talk to your doctor if you want to get pregnant. It's best to stop taking atorvastatin at least 3 months before you start trying for a baby.

    If you become pregnant while taking atorvastatin, stop taking the medicine and tell your doctor.

    Atorvastatin and breastfeeding

    It's not known if atorvastatin gets into breast milk, but it may cause problems for your baby. You may be able to stop atorvastatin while you breastfeed.

    Tell your doctor if you're trying to get pregnant, become pregnant, or if you're breastfeeding.

  8. Cautions with other medicines

    Some medicines affect the way atorvastatin works and can increase the risk of serious side effects.

    Medicines that may not mix well with atorvastatin include:

    If you're taking atorvastatin and need to take one of these medicines, your doctor may:

    • prescribe a lower dose of atorvastatin
    • prescribe a different statin medicine
    • recommend that you stop taking atorvastatin for a while

    Mixing atorvastatin with herbal remedies and supplements

    St John's wort, a herbal medicine taken for depression, reduces the amount of atorvastatin in your blood, so it doesn't work as well.

    Talk to your doctor if you're thinking about starting St John's wort, as it will change how well atorvastatin works.

    Tell your doctor and pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

  9. Common questions