Senna (Senokot)

  1. About senna

    Senna is a natural laxative made from the leaves and fruit of the senna plant. It is used to treat constipation (difficulty pooing).

    Senna comes as tablets and as a liquid that you swallow.

    It is available on prescription and to buy from pharmacies and supermarkets.

    It is also combined with other ingredients in constipation remedies such as Manevac and Senokot Dual Relief tablets.

  2. Key facts

    • Senna takes about 8 hours to work.
    • It's best to take senna at bedtime so it works overnight.
    • The most common side effects are stomach cramps and diarrhoea. These are usually mild and short-lived.
    • Do not take senna for more than a week. Long term use of senna can stop your bowel working properly on its own.
    • Pee may turn a red-brown colour while you take senna. This is harmless and returns to normal after treatment has finished.
  3. Who can and can't take senna

    Senna is safe to take for most adults.  

    Do not give senna to a child under 6 unless your doctor has said it's ok.

    Senna may not be suitable for everyone. To make sure senna is safe for you, tell your doctor or pharmacist before starting senna if you have:

  4. How and when to take it

    Take senna once a day at bedtime. You can take senna with or without food.

    The normal dose of senna tablets for constipation in:

    • adults and children aged 12 and over is 1 or 2 tablets at bedtime
    • children aged between 6 and 11 is a single tablet at bedtime

    The normal dose of senna syrup for constipation in:

    • adults and children aged 6 years and over is one or two 5ml spoonfuls at bedtime
    • children aged 2 to 5 years (only under medical supervision) is half to one 5ml spoonful at bedtime

    Liquid senna comes with a plastic cup or spoon to measure the dose. Do not use a kitchen spoon as it will not give the right amount. If you don't have a cup or spoon, ask your pharmacist for one.

    Senna takes about 8 hours to work. It's normal to take it at bedtime so it works overnight.

    Drink plenty of fluids (6 to 8 glasses a day) while you are taking senna or your constipation may get worse.

    What if I forget to take it?

    If you forget a dose of senna, don't worry, just take the next dose the following evening.

    Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

    What if I take too much?

    Taking an extra dose of senna by accident is unlikely to harm you.

    You may get stomach pain and diarrhoea but this should ease off within a day or 2.

    If you're worried, talk to your doctor or pharmacist. 

  5. Side effects

    Like all medicines, senna may cause side effects in some people, but many people have no side effects or only minor ones.

    Common side effects

    Common side effects, which happen in more than 1 in 100 people, are stomach cramps and diarrhoea. You are particularly likely to get stomach cramps and diarrhoea with senna if you have constipation related to irritable bowel syndrome.

    Your pee may turn a red-brown colour while you are taking senna. This is normal and returns to normal after treatment has ended.

    Talk to your doctor or pharmacist if the side effects bother you or don’t go away.

    Serious side effects

    A very rare but serious side effect of senna is a severe raised, red, itchy skin rash on any part or all of your body.

    If you get a severe skin rash, stop taking senna and tell your doctor straight away.

    Serious allergic reaction

    In rare cases, it’s possible to have a serious allergic reaction to senna.

    A serious allergic reaction is an emergency. Contact a doctor straight away if you think you or someone around you is having a serious allergic reaction.

    The warning signs of a serious allergic reaction are:

    • getting a skin rash that may include itchy, red, swollen, blistered or peeling skin
    • wheezing
    • tightness in the chest or throat
    • having trouble breathing or talking
    • swelling of the mouth, face, lips, tongue, or throat

    These are not all the side effects of senna. For a full list see the leaflet inside your medicines packet.

    You can report any suspected side effect to the UK safety scheme.

  6. How to cope with side effects

    What to do about:

    • diarrhoea - drink plenty of water or other fluids. It may also help to take oral rehydration solutions. You can buy these from a pharmacy to prevent dehydration. Reducing the dose of senna may also help diarrhoea. Don’t take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor
    • stomach cramps - if you get stomach cramps, reduce your dose of senna until it goes away
  7. Pregnancy and breastfeeding

    Constipation is common at the end of pregnancy and just after having a baby.

    If you're pregnant or breastfeeding, it's better to ease constipation without taking a medicine. Your doctor or midwife will first advise that you eat more fibre and drink plenty of liquids. You'll also be encouraged to do gentle exercise.

    If dietary and lifestyle changes don't work, you may be recommended a laxative.

    Laxatives are usually safe for pregnant women to take because most of them aren't absorbed by the digestive system. This means that your baby won't feel the effects of the laxative.

    Senna may not be suitable if you're pregnant or breastfeeding because it's partly absorbed by your gut.

    Lactulose and Fybogel are safer laxatives to take during pregnancy and while breastfeeding.

    Tell your pharmacist or doctor if you're trying to get pregnant, are already pregnant or if you're breastfeeding.

  8. Cautions with other medicines

    There are some medicines that do not mix well with senna and can change the way it works.

    Tell your doctor if you are taking these medicines before starting senna:

    • a heart medicine such as digoxin or quinidine
    • a diuretic (water tablet)
    • steroid tablets
    • liquorice root preparations

    Mixing senna with herbal remedies and supplements

    There are no known problems with taking herbal remedies and supplements with senna.

    However, for safety, speak to your pharmacist or doctor before taking senna if you routinely take any herbal or alternative remedies.

    Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

  9. Common questions

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